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OZONE SAFETY Links

OZOTOP – C0123 Ozone Safety Report.pdf    OZONE Safety – Professor Laurie Walsh – 23rd November, 2012

The Influence Of Ozonised Water On The Epithelial Wound Healing Process In The Oral Cavity.

It should be noted that the influence of ozone leads to a higher expression of cytokines that are important for wound healing, especially TGF-?1 (3), an important substance for regulation and coordination in the initial wound healing phase. TGF-?1 has a marked influence on cell proliferation, chemotaxis (monocytes and fibroblasts), angiogenesis, synthesis of extracellular matrix and collagen synthesis (4, 16, 170). Large studies performed in vitro and in vivo have showed that TGF-?1 leads to a pronounced acceleration of wound healing (2, 13, 16). One single application leads to clearly visible effects (12). This application though, must be performed immediately; 24 hours postoperatively the positive effect is completely lost (2). Andreas Filippi. Clinic of Oral Surgery, -Radiology and Oral Medicine University of Basel, Hebelstrasse 3, CH-4056 Basel, Switzerland

Researchers Explore Effect of Low-Dose Gaseous Ozone on Pathogenic Bacteria

http://www.infectioncontroltoday.com/news/2012/12/researchers-explore-effect-of-lowdose-gaseous-ozone-on-pathogenic-bacteria.aspx Treatment of chronically infected wounds is a challenge, and bacterial environmental contamination is a growing issue in infection control. Ozone may have a role in these situations. Fontes, et al. (2012) sought to determine whether a low dose of gaseous ozone/oxygen mixture eliminates pathogenic bacteria cultivated in Petri dishes.

A pilot study with six bacterial strains was conducted using different concentrations of ozone in an ozone-oxygen mixture to determine a minimally effective dose that completely eliminated bacterial growth. The small and apparently bactericidal gaseous dose of 20 mug/mL ozone/oxygen (1:99) mixture, applied for 5min under atmospheric pressure was selected. In the 2nd phase, eight bacterial strains with well characterized resistance patterns were evaluated in vitro using agar-blood in adapted Petri dishes (105 bacteria/dish). The cultures were divided into three groups: 1) ozone-oxygen gaseous mixture containing 20 mug of O3/mL for 5 minutes; 2) 100 percent oxygen for 5 minutes; 3) baseline, no gas was used. The selected ozone dose was applied to the following eight strains: Escherichia coli, oxacillin-resistant Staphylococcus aureus, oxacillin-susceptible Staphylococcus aureus, vancomycin-resistant Enterococcus faecalis, extended-spectrum beta-lactamase-producing Klebsiella pneumoniae, carbapenem-resistant Acinetobacter baumannii, Acinetobacter baumannii susceptible only to carbapenems, and Pseudomonas aeruginosa susceptible to imipenem and meropenem. All isolates were completely inhibited by the ozone-oxygen mixture while growth occurred in the other two groups. The researchers concluded that a single topical application by nebulization of a low ozone dose completely inhibited the growth of all potentially pathogenic bacterial strains with known resistance to antimicrobial agents. Their research was published in BMC Infectious Diseases. Reference: Fontes B, et al. Effect of low-dose gaseous ozone on pathogenic bacteria. BMC Infectious Diseases 2012, 12:358 doi:10.1186/1471-2334-12-358

 

Recent Death from Contaminated Dental Waterlines Demonstrates Life & Death Importance of Monitoring Water Quality

Ozone Therapy: A Possible Answer to Ebola? 

Ebola is heavily featured in the news these days, bringing lots of fear and concerns. Can anything be done to successfully treat or prevent this horrific and highly lethal disease?

Dr. Robert Rowen who is a leading expert on oxidative therapy, offers an intriguing answer in this interview. By invitation of the President of Sierra Leone, he’s going there to teach health care workers how to treat Ebola using ozone.

“I do ozone, ultraviolet blood irradiation therapy, and high-dose vitamin C,” he explains. “All of these collectively belong to a family of therapies called oxidative therapies.

In my opinion – and I’ve been doing them longer than any other living person in North America; since 1986 – especially ozone and ultraviolet [therapies] are among the most powerful therapies for healing across the board of anything I’ve ever seen in my career… It does so by stimulating your own body to heal.”

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OZONE Can Play a Key Role in HACCP Plans

Hazard Analysis and Critical Control Point (HACCP) plans can benefit by using OZONE Food Safety Solutions systems disinfection technology. MINT OZONE systems are designed with well-engineered ozone delivery technologies whose disinfection potential has been tested, measured and verified. Control modules built into MINT systems give food processors both information and flexibility to ensure that the ozone disinfection systems are operating effectively. FDA and USDA both support HACCP plans in even the smallest processing plants. According to the FDA, “HACCP is a management system in which food safety is addressed through the analysis and control of biological, chemical, and physical hazards from raw material production, procurement and handling, to manufacturing, distribution and consumption of the finished product”.

Ozone nano-bubble water Potential treatment for severe gum infections

nano-bubble

A powerful new antiseptic agent, called ozone nano-bubble water, holds promise for the treatment of periodontitis, or severe gum infections, according to research published in the journal Science and Technology of Advanced Materials.

The study, by Shinichi Arakawa and colleagues at Tokyo Medical and Dental University and Japan’s National Institute of Advanced Industrial Science and Technology, evaluated the bactericidal activities of ozone nano-bubble water — also known as NBW3 — against the two main bacterial agents that cause periodontitis as well as its toxicity to human oral tissue cells.

Their results showed that NBW3 can kill periodontal pathogens within 30 seconds of exposure, yet has only a minor impact on the viability of oral tissue cells after 24 hours of exposure.
Periodontitis is an inflammation of the oral tissues that surround and support our teeth — it is caused by bacteria residing in “biofilms” or dental plaque.

The traditional first step of periodontal treatment involves “mechanical debridement” (i.e. scraping away the dental plaque and dental calculus). Various antiseptics and antibiotics have been used to supplement mechanical debridement.

But antibiotic therapies have several significant drawbacks, such as the selectivity of antimicrobial action, possible development of resistant bacteria, and risk for adverse host reactions. For these reasons, the topical use of a low-cost, broad-spectrum antiseptic agent with low potential for adverse reactions is preferable.

One possible alternative is ozone (O3), which has strong antimicrobial activity against bacteria, fungi, protozoa and viruses, and does not induce microbial resistance. Aqueous ozone is highly biocompatible with oral tissue cells. However, ozonated water must be used within the first 5 to 10 minutes after production to assure its potency.

To address this obstacle, co-author M. Takahashi and K. Chiba developed a patented procedure to produce ozone nano-bubble water. NBW3 retains its oxidation ability for more than six months if protected from exposure to ultraviolet rays. Its high stability allows for the bottling and use of NBW3 as a disinfectant solution.

Based on their in vitro results, the researchers conclude that NBW3 could become a valuable tool for treating periodontitis. However, since in vitro models cannot be directly compared to real-life clinical situations in which oral antiseptics are diluted with saliva, the authors recommend further research to determine the extent to which NBW3’s potency may be reduced by the saliva of dental patients.

OZONE Kills Norovirus Sydney 2012  …destroyed by BioWell &BioSure!

Norovirus

OZONE in Dentistry – What is the fuss?

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WESTMEAD Oral Health General Clinic uses BioWell OZONE…

BioWell OZONE in Westmead General Dental ClinicBIOWELL cdsytBioWell OZONE in use at Westmead General Clinic

 BioWell Ozone Installed in Dr Sasha Rutnam’s new Surgery

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International Association Ozone Healthcare and Dentistry Congress – LV Feb, 2013

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Food Safety Sanitation Hygiene Chemical Free Sterilisation Green Environmentally Friendly Disinfection BioSure BioWell Safe Sustainable Prions Decontamination Sanitizer

Salmonella Listeria E. coli Noro Virus Cryptosporidium parvum dangerous antibiotic resistant staph bacteria (MRSA) (antibiotic resistant staph) threatening microorganisms such as Pseudomonas